Table 2.
Number and frequency of EIs in recent clinical trials for UC
| Survey period | Index | Validation | Number (%) |
|---|---|---|---|
| 1999–2008 (N = 147, including duplicates) | |||
| Baron score | Validated | 68 (46.2%) | |
| Rachmilewitz endoscopic index | Not validated | 35 (23.8%) | |
| Matts score | Not validated | 6 (4.1%) | |
| Tygat Endoscopic grading score | Unknown | 4 (2.7%) | |
| Others (Including original indices for the trial) | Not available | 34 (23.1%) | |
| 2009–2012 (N = 58, including duplicates) | |||
| Mayo Score (Including Mayo Endoscopic Sub-score) | Not validated | 25 (42.4%) | |
| DAI Score (Including Sutherland Index) | Not validated | 24 (40.7%) | |
| Rachmilewitz endoscopic index | Not validated | 5 (8.5%) | |
| Pouchitis Disease Activity Index (PDAI) | Not validated | 2 (3.4%) | |
| Matts Classification | Not validated | 2 (3.4%) | |
| Others (Including original indices for the trial) | Not available | 5 (8.5%) | |
| 2013–2017 (N = 126, including duplicates) | |||
| Mayo Score (Including Mayo Endoscopic Sub-score) | Not validated | 87 (69.0%) | |
| DAI Score (Including Sutherland Index) | Not validated | 25 (19.8%) | |
| Baron Score (Including modified Baron Score) | Validated | 7 (5.6%) | |
| Pouchitis Disease Activity Index (PDAI) | Not validated | 6 (4.8%) | |
| Rachmilewitz endoscopic index | Not validated | 6 (4.8%) | |
| Ulcerative Colitis Endoscopic Index of Severity (UCEIS) | Validated | 6 (4.8%) | |
| Matts Classification | Not available | 5 (4.0%) | |
DAI disease activity index, EIs endoscopic indices, UC ulcerative colitis