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. 2022 Mar 2;57(4):246–266. doi: 10.1007/s00535-022-01862-y

Table 3.

Number and frequency of CIs in recent clinical trials for CD (N = 377, including duplicates)

Survey period Clinical index Validation Number (%)
2009 to 2012 (N = 152, including duplicates)
Crohnʼs Disease Activity Index (CDAI) Validated 125 (82.2%)
Harvey–Bradshaw Index (Simple CDAI) Validated 23 (15.1%)
Pediatric Crohnʼs Disease Activity Index (PCDAI) Validated 7 (4.6%)
Perianal Crohnʼs Disease Activity Index Validated 3 (2.0%)
IOIBD Score (Oxford Score) Validated 2 (1.3%)
Others (Including original indices for the trial) Not available 8 (5.3%)
2013–2017 (N = 225, including duplicates)
Crohnʼs Disease Activity Index (CDAI) Validated 129 (57.3%)
Harvey–Bradshaw Index (Simple CDAI) Validated 38 (16.9%)
Pediatric Crohnʼs Disease Activity Index (PCDAI) Validated 35 (15.6%)
IOIBD Score (Oxford Score) Validated 2 (0.9%)
Others (Including original indices for the trial) Not available 16 (7.1%)
2009–2017 (N = 377, including duplicates)
Crohnʼs Disease Activity Index (CDAI) Validated 254 (67.4%)
Harvey–Bradshaw Index (Simple CDAI) Validated 61 (16.2%)
Pediatric Crohnʼs Disease Activity Index (PCDAI) Validated 42 (11.1%)
IOIBD Score (Oxford Score) Validated 4 (1.1%)
Perianal Crohnʼs Disease Activity Index Validated 3 (0.8%)
Others (Including original indices for the trial) Not available 24 (6.4%)

CIs Clinical indices, CD Crohn’s disease, IOIBD International Organization for the Study of Inflammatory Bowel Disease