Table 4.
Number and frequency of EIs in recent clinical trials for CD (N = 85, including duplicates)
| Survey period | Endoscopic index | Validation | Number (%) |
|---|---|---|---|
| 2009–2012 (N = 22, including duplicates) | |||
| Crohnʼs Disease Endoscopic Index of Severity (CDEIS) | Validated | 10 (45.5) | |
| Rutgeerts Score | Validated | 6 (27.3) | |
| Capsule Endoscopy Crohnʼs Disease Activity Index (CECDAI) | Validated | 3 (13.6) | |
| Simple Endoscopic Score for Crohnʼs Disease (SES-CD) | Validated | 2 (9.1) | |
| Others (Including original indices for the trial) | Not available | 5 (7.0) | |
| 2013–2017 (N = 63, including duplicates) | |||
| Simple Endoscopic Score for Crohnʼs Disease (SES-CD) | Validated | 31 (49.2) | |
| Rutgeerts Score | Validated | 23 (36.5) | |
| Crohnʼs Disease Endoscopic Index of Severity (CDEIS) | Validated | 19 (30.2) | |
| Lewis Score (Capsule Endoscopy Score) | Validated | 2 (3.2) | |
| Capsule Endoscopy Crohnʼs Disease Activity Index (CECDAI) | Validated | 1 (1.6) | |
| Others (Including original indices for the trial) | Not available | 2 (3.2) | |
| 2009 to 2017 (N = 85, including duplicates) | |||
| Simple Endoscopic Score for Crohnʼs Disease (SES-CD) | Validated | 33 (38.8) | |
| Crohnʼs Disease Endoscopic Index of Severity (CDEIS) | Validated | 29 (34.1) | |
| Rutgeerts Score | Validated | 29 (34.1) | |
| Capsule Endoscopy Crohnʼs Disease Activity Index (CECDAI) | Validated | 4 (4.7) | |
| Lewis Score (Capsule Endoscopy Score) | Validated | 2 (2.4) | |
| Others (Including original indices for the trial) | Not available | 4 (4.7) | |
EIs endoscopic indices, CD Crohn’s disease