Table 7.
Definitions of CI for UC
Index | Definition |
---|---|
Mayo Score | |
Remission |
≤ 1 [93, 94], ≤ 2 [5, 20, 21, 44, 93, 95–97], ≤ 2 and no subscore > 1 and rectal bleeding score = 0 [98–106], < 2 [5, 20, 21, 107, 108], < 4 and rectal bleeding = 0 and endoscopy ≤ 1 [5, 20, 21], < 4 [5, 20, 21] |
Response | ≥ Δ3 [95], ≥ Δ2 and ≥ 25% decrease with Δrectal bleeding ≥ 1 or ≤ 1 [101], > Δ3 and at least a 30% decrease [97,99] < 3 and ≥ Δ30% with Δrectal bleeding < 1 with rectal bleeding ≤ 1 [44, 93, 96, 100, 102–106], rectal bleeding ≤ 1 [106] |
Partial Mayo Score (p-MS) | |
Remission | ≤ 2 [5, 100, 106], < 2 [5], ≤ 2 with no subscore > 1 [98, 99], < 3 and no score > 1 [5] |
Response | ≥ 1 [99], ≥ Δ1 [99, 107], ≥ Δ2 [5, 20, 21, 99], ≥ Δ2 and ≥ Δ30% [100], > Δ2 [5, 20, 21], ≥ 2 and ≥ Δ25% with Δrectal bleeding subscore ≥ 1 or ≤ 1 [68], > Δ3 [5, 20, 21], ≥ Δ30% [5, 20, 21], ≥ Δ30% and Δeach sub-score ≥ 1 [5, 20, 21, 100] |
Sutherland Index (also known as Disease Activity Index, DAI) | |
Remission | = 0 [109–112], ≤ 1 [113, 114], ≤ 2 with no individual subscore > 1 [109, 115], ≤ 2 with subscore ≤ 1 [115], ≤ 3 [116] |
Improvement | ≥ Δ2 [110], ≤ Δ3 [112], ≥ Δ4 with improvement of all categorizes [109, 115] |
Modified DAI | |
Remission | = 0 [112] |
Improvement | ≤ Δ3 [112] |
Rachmilewitz Index (also known as Clinical Activity Index, CAI) | |
Remission | CAI ≤ 4 [24, 117–119] |
Response | CAI ≥ Δ1 [119] |
Improvement | CAI ≥ Δ3 [117, 118] |
Simple Clinical Colitis Activity Index (SCCAI) | |
Remission | ≤ 2 [5, 99] |
Response | Δ > 30% [5] |
Lichtiger Index | |
Remission | ≤ 4 [120, 121] |
Improvement | ≤ 10 and ≥ Δ3 [120] |
Pediatric Ulcerative Colitis Activity Index (PUCAI) | |
Remission | ≤ 10 points [5, 122] |
Response | ΔPUCAI≧20 [5] |
CI clinical index, UC ulcerative colitis