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. 2022 Mar 2;57(4):246–266. doi: 10.1007/s00535-022-01862-y

Table 7.

Definitions of CI for UC

Index Definition
Mayo Score
 Remission

 ≤ 1 [93, 94], ≤ 2 [5, 20, 21, 44, 93, 9597], ≤ 2 and no subscore > 1 and rectal bleeding score = 0 [98106],

 < 2 [5, 20, 21, 107, 108], < 4 and rectal bleeding = 0 and endoscopy ≤ 1 [5, 20, 21], < 4 [5, 20, 21]

 Response  ≥ Δ3 [95], ≥ Δ2 and ≥ 25% decrease with Δrectal bleeding ≥ 1 or ≤ 1 [101], > Δ3 and at least a 30% decrease [97,99] < 3 and ≥ Δ30% with Δrectal bleeding < 1 with rectal bleeding ≤ 1 [44, 93, 96, 100, 102106], rectal bleeding ≤ 1 [106]
Partial Mayo Score (p-MS)
 Remission  ≤ 2 [5, 100, 106], < 2 [5], ≤ 2 with no subscore > 1 [98, 99], < 3 and no score > 1 [5]
 Response  ≥ 1 [99], ≥ Δ1 [99, 107], ≥ Δ2 [5, 20, 21, 99], ≥ Δ2 and ≥ Δ30% [100], > Δ2 [5, 20, 21], ≥ 2 and ≥ Δ25% with Δrectal bleeding subscore ≥ 1 or ≤ 1 [68], > Δ3 [5, 20, 21], ≥ Δ30% [5, 20, 21], ≥ Δ30% and Δeach sub-score ≥ 1 [5, 20, 21, 100]
Sutherland Index (also known as Disease Activity Index, DAI)
 Remission  = 0 [109112], ≤ 1 [113, 114], ≤ 2 with no individual subscore > 1 [109, 115], ≤ 2 with subscore ≤ 1 [115], ≤ 3 [116]
 Improvement  ≥ Δ2 [110], ≤ Δ3 [112], ≥ Δ4 with improvement of all categorizes [109, 115]
Modified DAI
 Remission  = 0 [112]
 Improvement  ≤ Δ3 [112]
Rachmilewitz Index (also known as Clinical Activity Index, CAI)
 Remission CAI ≤ 4 [24, 117119]
 Response CAI ≥ Δ1 [119]
 Improvement CAI ≥ Δ3 [117, 118]
Simple Clinical Colitis Activity Index (SCCAI)
 Remission  ≤ 2 [5, 99]
 Response Δ > 30% [5]
Lichtiger Index
 Remission  ≤ 4 [120, 121]
 Improvement  ≤ 10 and ≥ Δ3 [120]
Pediatric Ulcerative Colitis Activity Index (PUCAI)
 Remission  ≤ 10 points [5, 122]
 Response ΔPUCAI≧20 [5]

CI clinical index, UC ulcerative colitis