HNRNPM expression is increased in HCC and fetal liver tissues and is associated with prognosis.A, Normalized (Norm) HNRNPM expression levels during mouse liver development from GSE57824 data. B, HNRNPM expression levels during mouse liver development from GSE13149 data. C, Western blot analysis of HNRNPM protein levels in human fetal liver and adult liver tissues. D, Real-time qPCR analysis of HNRNPM mRNA levels in human fetal liver and adult liver tissues. Data are mean ± standard deviation of n = 3 independent samples. ∗P < .05; ∗∗P < .01; ∗∗∗P < .001; ∗∗∗∗P < .0001 by the Student t test. E, Norm HNRNPM expression in HCC and normal liver tissues. ∗∗P < .01 by the Student t test. F, Real-time qPCR analysis of HNRNPM mRNA levels in 60 paired HCC and normal liver tissues. G, Representative images of HNRNPM by IHC in HCC and normal tissues. H, Kaplan-Meier analysis of HNRNPM in HCC cohort. I, Kaplan-Meier analysis of HNRNPM in TCGA cohort.