HNRNPM was associated with clinopathological characteristics and poor prognosis in patients with HCC.A, Oncomine analysis showed the prognostic splicing factors from TCGA datasets. B, The selected prognostic splicing factors validated by real-time PCR in portal vein tumor thrombosis (PVTT) HCC, non-PVTT HCC, and normal liver tissues. C, The HNRNPM protein expression in metastasis and metastasis-free HCC tissues. D, The HNRNPM protein expression in tumor grade I/II and III/IV. E, The HNRNPM protein expression in no-microvascular invasion and microvascular invasion HCC tissues. F, The relative HNRNPM expression in tumor stage I/II/III/IV. G, The correlation analysis between Ki-67 and HNRNPM in TCGA database. H, Kaplan-Meier analyses of the correlations between HNRNPM level and overall survival in HCC tumor stage I/II and III/IV from our HCC cohort. I, Kaplan-Meier analyses of the correlations between HNRNPM level and OS in HCC tumor grade I/II and III/IV from our HCC cohort.