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. 2022 Feb 12;13(5):1413–1447. doi: 10.1016/j.jcmgh.2022.02.006

Figure 5.

Figure 5

HNRNPM drives HCC tumorigenesis and maintains CSC properties.A-B, Sphere formation and limiting dilution assays when overexpressed HNRNPM in MHCC97L and HepG2 cells. ∗P < .05; ∗∗P < .01 by the Student t test. The number of spheroids formed as a fraction of the number of cells seeded per well is given. Data are from 3 independent experiments. C-D, Cell cycle detected by flow cytometry when overexpressed HNRNPM in MHCC97L and HepG2 cells. ∗P < .05; ∗∗P < .01 by the Student t test. E-F, Colony formation assay when overexpressed HNRNPM in MHCC97L and HepG2 cells. ∗P < .05; ∗∗P < .01 by the Student t test. G-H, Cell migration assay when overexpressed HNRNPM in MHCC97L and HepG2 cells. ∗P < .05 by the Student t test. I, Cell invasion assays when overexpressed HNRNPM in MHCC97L and HepG2 cells. Results are presented as mean ± standard error of the mean, n = 3. ∗P < .05 by the Student t test.