Table 2.
The Association of HNRNPM Expression With Clinical Characteristics in 371 Patients With HCC
| Parameters | HNRNPM Low expression | HNRNPM High expression | P-value |
|---|---|---|---|
| Number of patients | 185 | 186 | |
| BMI, kg/m2 | 26.4 ± 6.1 | 25.9 ± 10.4 | .066 |
| Albumin, g/dL | 4.3 ± 4.7 | 4.4 ± 5.2 | .929 |
| Creatinine, mg/dL | 1.1 ± 1.2 | 1.4 ± 1.8 | .008 |
| Platelet count, ×104 | 213.0 ± 114.0 | 232.1 ± 99.6 | .071 |
| Prothrombin time, s | 3.8 ± 4.4 | 3.7 ± 4.3 | .279 |
| Sex | .160 | ||
| Female | 54 (29.2) | 67 (36.0) | |
| Male | 131 (70.8) | 119 (64.0) | |
| AJCC stage | .009 | ||
| I/II | 138 (80.2) | 119 (68.0) | |
| III/IV | 34 (19.8) | 56 (32.0) | |
| Tumor grade | .017 | ||
| I | 32 (17.5) | 23 (12.6) | |
| II | 97 (53.0) | 80 (43.7) | |
| III/IV | 54 (29.5) | 80 (43.7) | |
| Embolization performed | .343 | ||
| No | 5 (21.7) | 6 (35.3) | |
| Yes | 18 (78.3) | 11 (64.7) | |
| Child-Pugh grade | .481 | ||
| A | 111 (93.3) | 77 (90.6) | |
| B | 8 (6.7) | 8 (9.4) | |
| Virus status | .782 | ||
| HBV | 39 (86.7) | 50 (84.7) | |
| HCV | 6 (13.3) | 9 (15.3) | |
| Ki-67 | < .001 | ||
| Low expression | 137 (74.1) | 48 (25.8) | |
| High expression | 48 (25.9) | 138 (74.2) | |
| Recurrence sites | .059 | ||
| Liver | 63 (82.9) | 53 (66.2) | |
| Lung | 6 (7.9) | 12 (15.0) | |
| Other | 7 (9.2) | 15 (18.8) |
Note: Data are presented as number (%) or mean ± standard deviation.
Note: Boldface P values indicate statistical significance.
AJCC, American Joint Committee on Cancer; BMI, body mass index; HBV, hepatitis B virus; HCC, hepatocellular carcinoma; HCV, hepatitis C virus; HNRNPM, heterogeneous nuclear ribonucleoprotein M.