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. 2022 Feb 17;47(5):1128–1136. doi: 10.1038/s41386-022-01293-6

Table 1.

Clinical and demographic measures.

  p Value
Characteristic CN (n = 118) MCI (n = 44) AD (n = 28) CN vs. AD CN vs. MCI MCI vs. AD
Age, mean (SD), y 72.3 (5.7) 73.2 (5.4) 67.4 (8.9) <0.001 0.70 0.03
Male, No. (%) 36 (30.5) 21 (47.7) 12 (42.9) 0.21 0.03 0.62
Education, mean (SD), y 15.5 (3.6) 14.1 (3.4) 15.0 (3.7) 0.54 0.07 0.46
CDR score, mean (SD) 0.0 (0) 0.5 (0) 0.9 (0.5) <0.001 n/a <0.001
MMSE score, mean (SD) 29.2 (0.9) 28.0 (1.8) 20.9 (5.9) <0.001 <0.001 <0.001
MBI score, mean (SD) 2.3 (5.5) 7.6 (8.5) 13.0 (9.8) <0.001 <0.001 0.04
Tau-positive, No. (%) 10 (8.5) 22 (48.9) 25 (89.3) <0.001 <0.001 <0.001

p values are from t-tests for continuous measures and chi-square tests for categorical measures.