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. 2022 Mar 21;8:30. doi: 10.1038/s41531-022-00282-2

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — a Violin plot shows the magnitude of T cell response (sum of IFN-γ, IL-5, and IL-10) in HC non-responders (HC_NR) (n = 20) PD responders (PD_R) (n = 15), and PD non-responders (PD_NR) (n = 21). The dotted line denotes the cut-off value of 250 SFC. Two-tailed Mann–Whitney, ****p < 0.0001. b The gating strategy was adopted to identify and sort PBMC, CD4, and CD8 memory T cells from PD and HC subjects.