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. 2022 Mar 21;13:1514. doi: 10.1038/s41467-022-28909-1

Table 1.

Distribution of undiagnosed and diagnosed participants in three trajectories over sex and HLA.

Undiagnosed Diagnosed
TR1(n = 483) TR2
(n = 257)
TR3
(n = 762)
TR1
(n = 256)
TR2
(n = 273)
TR3
(n = 114)
Sex Male 283 (59%) 145 (56%) 409 (54%) 155 (61%) 146 (53%) 52 (46%)
Female 200 (41%) 112 (44%) 353 (46%) 101 (39%) 127 (47%) 62 (54%)
HLA-DR status DR3/4 73 (15%) 48 (19%) 141 (19%) 93 (36%) 106 (39%) 41 (36%)
DR4/X 298 (62%) 140 (54%) 421 (55%) 139 (54%) 138 (51%) 55 (48%)
DR3/X 70 (14%) 23 (9%) 85 (11%) 15 (6%) 19 (7%) 16 (14%)
DRX/X 42 (9%) 45 (18%) 112 (15%) 9 (4%) 10 (4%) 2 (2%)
Unknown 0 (0%) 1 (0%) 3 (0%) 0 (0%) 0 (0%) 0 (0%)
Age of seroconversion 5.38 ± .51 6.28 ± .64 6.93 ± .38 3.48 ± .41 2.52 ± .25 4.71 ± .59
Age of diagnosis 7.64 ± .52 7.11 ± .54 10.46 ± .69

Distribution of undiagnosed and diagnosed participants in three trajectories over sex and HLA-DR status; age (mean ± standard deviation) of seroconversion and diagnosis for undiagnosed and diagnosed participants.