Fig. 1. Summary of participants. (A) Participants were selected as those with complete and valid data during the follow-up period from all participants enrolled in the LGS. (B) Participants were divided into four subgroups; idiopathic IGHD, idiopathic MPHD, organic IGHD, and organic MPHD.

LGS = LG Growth Study, GHD = growth hormone deficiency, IGHD = isolated growth hormone deficiency, MPHD = multiple pituitary hormone deficiency.