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. 2022 Mar 15;37(11):e90. doi: 10.3346/jkms.2022.37.e90

Table 2. Differences in pituitary hormone deficiency between the idiopathic and organic GHD groups.

GHD types Total (N = 163) Idiopathic GHD (n = 131) Organic GHD (n = 32) P valuea
Isolated GHD vs. MPHD < 0.001
Isolated GHD 129 (79.1) 120 (91.6) 9 (28.1)
MPHD 34 (20.9) 11 (8.4) 23 (71.9)
No. of MPHD 0.045
GHD + 1 pituitary deficiency 10 (6.1) 6 (4.6) 4 (12.5)
GHD + 2 pituitary deficiencies 6 (3.7) 3 (2.3) 3 (9.4)
GHD + 3 pituitary deficiencies 9 (3.7) 1 (0.8) 8 (25.0)
GHD + 4 pituitary deficiencies 9 (5.5) 1 (0.8) 8 (25.0)
Types of MPHD (except GHD) 0.283
TSHD 32 (19.6) 10 (7.6) 22 (68.8)
ACTHD 26 (16.0) 5 (3.8) 21 (65.6)
CDI 21 (12.9) 2 (1.5) 19 (59.4)
LH/FSHD 13 (8.0) 2 (1.5) 12 (37.5)

All values are presented as measured number (percentage).

GHD = growth hormone deficiency, MPHD = multiple pituitary hormone deficiency, TSHD = thyroid stimulating hormone deficiency, ACTHD = adrenocorticotropic hormone deficiency, CDI = central diabetes insipidus, LH/FSHD = hypogonadotropic hypogonadism.

aP values are calculated with χ2 test.