Table 3. Medication Abortion Additional Interventions and Major Adverse Events.
| Intervention/adverse event | No. | % (95% CI) | |
|---|---|---|---|
| Unadjusted rate | Adjusted imputed ratea | ||
| Effectiveness | |||
| No. | NA | 2397 | 3779 |
| Complete abortion without known interventionb | 2272 | 94.5 (92.9-96.1) | 94.8 (93.6-95.9) |
| Intervention to complete abortionc,d | 116 | 5.1 (3.7-6.5) | 4.6 (3.7-5.5) |
| Aspiration, second trimester abortion procedure, or surgerye | 88 | 3.8 (2.8-4.8) | 3.6 (2.7-4.4) |
| Prescribed >1600 μg of misoprostol, mifepristone, or other medications | 37 | 1.7 (0.7-2.8) | 2.5 (1.5-3.6) |
| Treatment for ectopic pregnancy | 4 | 0.17 (0.00-0.33) | 0.22 (0.00-0.45) |
| Continuing viable pregnancy without known intervention | 9 | 0.34 (0.00-0.74) | 1.27 (0.00-2.64) |
| Safety | |||
| No. | NA | 2825 | 3779 |
| No major abortion-related adverse events | 2813 | 99.6 (99.3-99.8) | 99.5 (99.1-99.8) |
| Major abortion-related adverse events2 | 12 | 0.42 (0.18-0.66) | 0.54 (0.18-0.90) |
| Blood transfusion | 8 | 0.28 (0.02-0.53) | 0.40 (0.08-0.73) |
| Other major surgery, including treatment of ectopic pregnancy | 3 | 0.11 (0.00-0.23) | 0.23 (0.00-0.51) |
| Hospital admission | 6 | 0.21 (0.04-0.38) | 0.21 (0.04-0.38) |
Abbreviation: NA, not applicable.
Adjusted rates were calculated from mixed-effects logistic regression models fit to imputed data and adjusted for age, race and ethnicity, residence, prior medication abortion, participation in the TelAbortion Study, method of mifepristone provision, and pregnancy duration, with the exception of rare outcomes (n ≤ 9), which were not adjusted to facilitate model convergence.
Includes patients who received 800 μg of misoprostol initially followed by a single additional dose of 800 μg of misoprostol. One of these patients had a continuing viable pregnancy after the first dose and then aborted after the second.
Includes 36 continuing viable pregnancies after initial treatment. In total, there were 46 (1.7%; 95% CI, 1.1%-2.2%) continuing viable pregnancies after initial medications were dispensed.
Intervention and safety categories are not mutually exclusive because multiple interventions or treatments may have been provided for a single abortion.
Includes 2 dilation and evacuation procedures and 1 salpingectomy.