Storch 2011.
Trial name or title | 1/2 D‐cycloserine Augmentation of CBT for Pediatric OCD |
Methods | Randomised double‐blind placebo controlled trial |
Participants | 150 youths aged 7 to 17 years with obsessive compulsive disorder and a CY‐BOCS score ≥ 16 and Full Scale IQ ≥ 85 as assessed will be included |
Interventions | To examine the relative benefit of 10 cognitive and behavioural therapies sessions of which sessions 4 to 10 will be augmented with weight‐adjusted doses of DCS (25, 50 mg) compared to CBT augmented with placebo in paediatric OCD |
Outcomes | CY‐BOCS, CGI |
Starting date | June 2011 |
Contact information | estorch@health.usf.edu |
Notes | Study ID: NCT01411774 |
(YBOC‐S) Yale Brown Obsessive Compulsive Scale, (OCI‐R) Obsessive Compulsive Scale ‐ Revised, (MADRS‐S) Montgomery Asberg Depression Rating Scale Self‐rating, (CGI) Clinical Global Impression Scale, (GAF) Global assessment of Functioning Scale, CAPS (Clinician Administered PTSD Scale), (AAVQ) Acrophobia Questionnaire With Avoidance, (ATHQ) Attitudes Towards Heights Questionnaire, (BAT) Behavioral Avoidance Test, (ADIS‐ IV) Anxiety Disorders Interview Schedule‐IV, (BDI‐II) Beck's Depression Inventory, (MADRS) Montgomery‐ Asberger Depression rating scale, (STAXI‐2) State Trait Anger Expression Inventory, (PSS‐SR) Post‐Traumatic Stress Symptom Self‐Report Scale, (QLI) Quality of Life Inventory, (STAI) State‐Trait Anxiety Inventory