Table 3.

The top 15 hypermethylated genes in field cancerization

Gene	log2 (Fold change)	P value	adjusted p value
ZSCAN31	5.079	< 0.001	< 0.001
ZNF345	4.431	0.040	0.022
DRD4	4.312	< 0.001	< 0.001
RAI1	4.097	< 0.001	< 0.001
ZNF132	4.083	< 0.001	< 0.001
ZNF175	3.870	0.040	0.023
ZNF43	3.861	0.016	0.002
SNX32	3.847	< 0.001	< 0.001
FAM19A2	3.742	< 0.001	< 0.001
HIST1H2BE	3.651	0.040	0.007
FABP5	3.541	0.040	0.010
NTMT1	3.501	0.040	0.040
ENPP2	3.440	0.040	0.032
KCNA3	3.401	0.035	0.005
CDO1	3.395	< 0.001	< 0.001