Table 2.
Factors associated with 90-day mortality for all patients admitted with colon cancer in 1980–2016; n = 1530
| Factors | Unadjusted odds ratio (95% CI) |
P value | Adjusted odds ratio (95% CI) |
P value |
|---|---|---|---|---|
| Age (years) | ||||
| < 65 | 1 (reference) | 1 (reference) | ||
| 65—74 | 1.44 (0.84 to 2.44) | 0.18 | 1.41 (0.74 to 2.69) | 0.30 |
| 75 – 79 | 1.78 (1.01 to 3.13) | 0.045 | 1.92 (0.95 to 3.88) | 0.070 |
| 80—84 | 3.69 (2.20 to 6.18) | < 0.001 | 2.64 (1.35 to 6.16) | 0.005 |
| 85 – 89 | 5.20 (2.91 to 9.30) | < 0.001 | 2.42 (1.11 to 5.29) | 0.027 |
| ≥ 90 | 11.38 (5.70 to 22.72) | < 0.001 | 5.85 (2.30 to 14.87) | < 0.001 |
| Calendar year | 0.97 (0.96 to 0.98) | < 0.001 | 0.94 (0.92 to 0.96) | < 0.001 |
| Female sex | 0.76 (0.57 to 1.03) | 0.072 | 0.76 (0.52 to 1.13) | 0.18 |
| CCI | 1.65 (1.39 to 1.95) | < 0.001 | 1.39 (1.10 to 1.77) | 0.006 |
| ASA score | ||||
| 1–2 | 1 (reference) | 1 (reference) | ||
| 3 | 2.82 (1.98 to 4.05) | < 0.001 | 1.92 (1.21 to 3.06) | 0.006 |
| 4–5 | 21.59 (13.26 to 35.14) | < 0.001 | 6.94 (3.69 to 13.05) | < 0.001 |
| Anaemiaa | 1.44 (1.06 to 1.96) | 0.019 | 1.19 (0.78 to 1.83) | 0.42 |
| Emergency surgery | 3.12 (2.23 to 4.35) | < 0.001 | 4.90 (2.99 to 8.05) | < 0.001 |
| Localization (left vs. right) | 0.87 (0.64 to 1.17) | 0.35 | 0.78 (0.52 to 1.18) | 0.24 |
| TNM-stage | ||||
| I | 1 (reference) | 1 (reference) | ||
| II | 2.72 (1.06 to 6.99) | 0.038 | 1.60 (0.54 to 4.74) | 0.39 |
| III | 1.17 (0.63 to 4.89) | 0.29 | 1.30 (0.40 to 4.23) | 0.67 |
| IV | 17.61 (7.06 to 43.92) | < 0.001 | 5.29 (1.57 to 17.80) | 0.007 |
| Unknown | 32.71 (11.51 to 92.99) | < 0.001 | 1.78 (0.46 to 6.86) | 0.40 |
| Treatment intent categories | ||||
| Curative intent | ||||
| Major resection | 1 (reference) | 1 (reference) | ||
| Polypectomy | 0.59 (0.08 to 4.43) | 0.59 | 1.59 (0.18 to 13.92) | 0.68 |
| Non-curative intent | ||||
| Major resection | 5.03 (3.20 to 7.91) | < 0.001 | 1.28 (0.55 to 9.98) | 0.56 |
| Bypass/stoma | 28.80 (16.22 to 50.83) | < 0.001 | 10.23 (4.03 to 26.00) | < 0.001 |
| Best supportive care | 19.78 (12.95 to 30.21) | < 0.001 | 9.56 (4.21 to 21.71) | < 0.001 |
Results are from a logistic regression analysis, with death within 90 days as dependent variable; unadjusted: analysis performed with one covariate at a time; adjusted: analysis performed with all listed covariates included simultaneously. CCI Charlson Comorbidity Index, classified in three levels: 0, 1 and 2 + ; aAnaemia was defined as < 13 g/dL in males and < 12 g/dL in women (based on WHO recommendations)