Table 5 .

Factors associated with postoperative complications^a after major resections with curative intent (R0 and R1); n = 1021^b

Factors	Unadjusted odds ratio (95% CI)	P value	Adjusted odds ratio (95% CI)	P value
Age (years)
< 65	1 (reference)		1 (reference)
65—74	1.51 (1.08 to 2.11)	0.016	1.35 (0.94 to 1.96)	0.11
75 – 79	2.13 (1.47 to 3.08)	< 0.001	1.51 (0.99 to 2.28)	0.053
80—84	2.83 (1.93 to 4.17)	< 0.001	1.96 (1.27 to 3.03)	0.002
85 – 89	2.96 (1.73 to 5.03)	< 0.001	2.14 (1.18 to 3.87)	0.013
≥ 90	7.60 (3.11 to 18.58)	< 0.001	5.36 (2.11 to 13.61)	< 0.001
Female sex	0.99 (0.78 to 1.25)	0.95	1.15 (0.89 to 1.49)	0.28
Calendar year
1980–1989	1 (reference)		1 (reference)
1990–1999	0.46 (0.32 to 0.67)	< 0.001	0.44 (0.30 to 0.66)	< 0.001
2000–2009	0.43 (0.30 to 0.60)	< 0.001	0.50 (0.33 to 0.94)	0.001
2010–2016	0.47 (0.33 to 0.68)	< 0.001	0.61 (0.40 to 0.94)	0.025
ASA score
1–2	1 (reference)		1 (reference)
3	2.00 (1.56 to 2.56)	< 0.001	1.43 (1.08 to 1.90)	0.013
4–5	19.07 (9.56 to 38.05)	< 0.001	10.86 (5.19 to 22.73)	< 0.001
Emergency surgery	2.51 (1.75 to 3.60)	0.001	2.30 (1.57 to 3.39)	< 0.001
Anaemia (g/dL haemoglobin)
Female ≥ 12.0, Male ≥ 13.0	1 (reference)		1 (reference)
Female 10–11.9, Male 11–12.9	1.97 (1.47 to 2.64)	< 0.001	2.26 (1.64 to 3.11)	< 0.001
Female < 10, Male < 11	4.76 (3.53 to 6.43)	< 0.001	5.61 (4.01 to 7.84)	< 0.001
Surgery duration (minutes)
< 90	1 (reference)		1 (reference)
90–179	1.01 (0.73 to 1.38)	0.96	0.96 (0.67 to 1.39)	0.84
≥ 180	2.24 (1.48 to 3.38)	0.001	1.52 (0.89 to 2.58)	0.13
Blood loss (mL)
0–200	1 (reference)		1 (reference)
201–400	1.21 (0.88 to 1.65)	0.24	1.48 (1.04 to 3.11)	0.029
401–800	1.67 (1.20 to 2.32)	0.002	2.16 (1.45 to 3.21)	< 0.001
> 800	3.69 (2.41 to 5.65)	< 0.001	4.13 (2.44 to 7.01)	< 0.001

^aComplications were classified according to Clavien-Dindo grades; ^bPatients included those with stages I-III colon cancer during 1980–2016