Table 6.
Factors associated with 90-day mortality after major resections with curative intent (R0 or R1); n = 1021a
| Factor | Dead within 90 days (%) | Unadjusted odds ratio (95% CI) | P value | Adjusted odds ratio (95% CI) | P value |
|---|---|---|---|---|---|
| Age (years) | |||||
| < 65 | 1/233 (0.4) | ┐ | |||
| 65 – 74 | 8/327 (2.4) | ├ 1 (reference) | 1 (reference) | ||
| 75 – 79 | 6/201 (3.0) | ┘ | |||
| 80 – 84 | 13/171 (7.6) | 4.09 (1.91 to 8.77) | < 0.001 | 3.90 (1.60 to 9.52) | 0.003 |
| 85 – 89 | 9/66 (13.6) | 7.85 (3.29 to 18.73) | < 0.001 | 10.72 (3.74 to 30.71) | < 0.001 |
| ≥ 90 | 8/23 (34.8) | 26.52 (9.77 to 72.01) | 19.76 (5.53 to 70.5) | < 0.001 | |
| Female sex | 0.54 (0.29 to 0.9976) | 0.049 | 0.51 (0.24 to 1.08) | 0.077 | |
| Calendar year | |||||
| 1980-1989 | 12/175 (6.8) | 1 (reference) | 1 (reference) | ||
| 1990-1999 | 12/241 (5.0) | 0.71 (0.31 to 1.62) | 0.42 | 0.49 (0.17 to 1.38) | 0.18 |
| 2000-2009 | 10/334 (3.0) | 0.42 (0.18 to 0.99) | 0.048 | 0.29 (0.09 to 0.84) | 0.022 |
| 2010-2016 | 11/271 (4.1) | 0.57 (0.25 to 1.33 | 0.20 | 0.45 (0.17 to 1.20) | 0.11 |
| ASA score | 3.77 (2.12 to 6.69) | < 0.001 | |||
| 1–2 | 10/591 (1.7%) | 1 (reference) | 1 (reference) | ||
| 3 | 20/395 (5.1%) | 3.10 (1.43 to 6.69) | 0.004 | 1.51 (0.63 to 3.59) | 0.35 |
| 4 | 15/35 (42.9%) | 43.58 (17.44 to 108) | < 0.001 | 12.60 (4.26 to 37.25) | < 0.001 |
| Emergency surgery | 10.24 (5.50 to 19.09) | < 0.001 | 6.80 (3.24 to 14.28) | < 0.001 |
aPatients included those with stages I-III colon cancer during 1980–2016; results are from a logistic regression analysis, with death as the dependent variable; unadjusted: performed with one covariate at a time; adjusted: performed with all listed covariates included simultaneously