Table 2.
Grade of adverse events in the patients receiving CAR T cells infusion
| Patient no. | 1 | 2 | 3 | 4 |
|---|---|---|---|---|
| CRS | 3 | 0 | 1 | 1 |
| Neurologic events | ||||
| Depressed level of consciousness | 1 | |||
| Dysphasia | 1 | |||
| Tremor | 1 | |||
| Hematologic events | ||||
| Thrombocytopenia | 4 | 1 | ||
| Anemia | 3 | 2 | 1 | |
| Neutropenia | 4 | 1 | 4 | 3 |
| Other non-hematologic events | ||||
| Diarrhea | 1 | |||
| Fever | 2 | 2 | 2 | |
| Vomiting | 1 | |||
| Nausea | 1 | |||
| Muscle or bone pain | 1 | |||
| Infection | 3 | 3 | 3 | 3 |
| Hypotension | 2 | 1 | 1 | |
| Elevated aminotransferases | 1 | |||
| Elevated blood bilirubin | 2 | 1 | 2 | |
| Hypokalemia | 1 | 1 | ||
| Hypocalcemia | 1 | 1 | 2 | |
| Hypoalbuminemia | 2 | 1 | ||
| Hypofibrinogenemia | 3 | |||
| Prolonged APTT | 1 | 1 |