Table 1.

Infection and the egress rates of mature schizont isolated from cultures treated with R406 (1.0 and 2.5 μM)

	Control		[R406] (1 µM)		[R406] (2.5 µM)
	No shear stress	Shear stress	No shear stress	Shear stress	No shear stress	Shear Stress
Infection rate	3.48 ± 0.96	4.24 ± 1.21	0.63 ± 0.25	2.6 ± 0.83	0.13 ± 0.06	0.30 ± 0.39
Egress rate	6.60 ± 2.41	9.37 ± 3.10	1.12 ± 0.84	3.9 ± 1.11	0.27 ± 0.48	1.09 ± 1.16

A portion of the schizonts were subjected to a rapid shear stress treatment to test its effect on the infection and egress rates. Results are the mean of 3 independent experiments (± SD) and expressed as number of released merozoites (egress rate) or number of infected RBC (infection rate) per each schizont present in the culture (no shear stress/shear stress).

Infection rate, RBC infected per schizont; egress rate, merozoites released per schizont.