TABLE 5.

Nature and incidence of treatment-related side effects in children treated with fluconazole, by age group

Organ system affected	No. (%) of patients with side effects	No. of side effects by age group
		6 mo–2 yr (n = 78)	2–5 yr (n = 133)	5–14 yr (n = 273)	≥14 yr (n = 36)	Totala (n = 562)
Total	58 (10.3)	8	17	44	11	80
Gastrointestinal	43 (7.7)	6	10	34	7	57
Skin	7 (1.2)	1	2	2	2	7
Special sensesb	5 (0.9)	0	0	3	2	5
Liver and biliary	3 (0.5)	1	1	1	0	3
Cardiovascular	2 (0.4)	0	0	2	0	2
Central and peripheral nervous	2 (0.4)	0	1	1	0	2
Respiratory	1 (0.2)	0	2	0	0	2
Hemopoietic	1 (0.2)	0	1	0	0	1
General	1 (0.2)	0	0	1	0	1

^aNo side effects were reported in infants aged less than 6 months (n = 42). 

^bTaste perversion (four patients) and deafness (one patient).