Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Feb 24;42(4):428–443. doi: 10.1161/ATVBAHA.121.317365

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2022 The Authors.

Arteriosclerosis, Thrombosis, and Vascular Biology is published on behalf of the American Heart Association, Inc., by Wolters Kluwer Health, Inc. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution, and reproduction in any medium, provided that the original work is properly cited.

PMC Copyright notice

Figure 7. — Marked macrophage infiltration and increased rate of proliferation in the adventitia of the vascular lesions. Cryosections of mesenteric arteries from Ctrl (control) or Y/T KO (YAP/TAZ [yes-associated protein 1/WW domain containing transcription regulator 1] knockout) mice treated with Ang II (angiotensin II) or vehicle. A, Immunostaining for Mac2 (galectin 3) demonstrates pronounced infiltration of monocytes/macrophages in the adventitia of hypertensive Y/T KO vascular lesions. B, The thickened adventitia of Y/T KO vascular lesions is associated with intense cell proliferation (Ki-67), whereas the media displays no obvious signs of cell proliferation. DAPI (4′,6-diamidino-2-phenylindole) was used as a nuclear stain. Elastin autofluorescence is shown in green. H&E indicates hematoxylin and eosin.