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. 2022 Feb 1:eabl6141. doi: 10.1126/scitranslmed.abl6141

Table 1. Characteristics of vaccinated patients.

n (%) or median [IQR] Non-responders
N = 23
Responders
N = 6
p*
Age (y) 61.2 [45.8; 70.1] 47.7 [41.2; 61.7] 0.254
Male 14 (61) 4 (67) >0.999
BMI 24.9 [23.8; 29.4] 23.8 [20.2; 24.5] 0.138
Comorbidities
Cardiopathy
Diabetes
15 (65)
3(13)
6 (100)
0 (0)
0.138
>0.999
Time since transplantation (y) 7.0 [1.6; 15.9] 10.4 [3.5; 24.6] 0.414
Donor type
Deceased
Living
20 (87)
3 (13)
5 (83)
1 (17)
>0.999
Induction therapy
Anti-thymocyte globulins
Basiliximab
No induction
NA
13 (57)
8 (35)
1 (4)
1 (4)
4 (67)
1 (17)
1 (17)
0 (0)
0.453
Maintenance immunosuppression
CNI (yes)
MMF/MPA (mg/day)
Steroids (mg/day)
imTOR (yes)
Belatacept (yes)
22 (96)
1000 [500; 1000]
5.0 [0.0; 5.0]
1 (4)
1 (4)
6 (100)
250 [0; 625]
2.5 [0.0; 5.0]
2 (33)
0 (0)
>0.999
0.014
0.358
0.100
>0.999
Biological data
Lymphocytes (G/L)
Monocytes (G/L)
CRP (mg/L)
Albumin (g/L)
Creatinine (μmol/L)
1.16 [0.99; 1.38]
0.55 [0.41; 0.79]
4.0 [4.0; 5.8]
43 [42; 46]
134 [97; 183]
1.99 [1.45; 2.66]
0.51 [0.44; 0.70]
4.5 [4; 10.6]
44 [43; 45]
131 [97; 237]
0.069
0.723
0.570
0.874
0.859

*qualitative variables were compared using a Fisher or Chi-square test, quantitative variables were compared using a Mann-Whitney test. IQR: interquartile range; y, years; BMI, body mass index; NA, not available; CNI: calcineurin inhibitor; MMF/MPA: mycophenolate mofetil/mycophenolic acid; imTOR, inhibitor of the mechanistic target of rapamycin; CRP, C-reactive protein.