Table 1. Characteristics of vaccinated patients.
n (%) or median [IQR] |
Non-responders
N = 23 |
Responders
N = 6 |
p* | |
Age (y) | 61.2 [45.8; 70.1] | 47.7 [41.2; 61.7] | 0.254 | |
Male | 14 (61) | 4 (67) | >0.999 | |
BMI | 24.9 [23.8; 29.4] | 23.8 [20.2; 24.5] | 0.138 | |
Comorbidities Cardiopathy Diabetes |
15 (65) 3(13) |
6 (100) 0 (0) |
0.138 >0.999 |
|
Time since transplantation (y) | 7.0 [1.6; 15.9] | 10.4 [3.5; 24.6] | 0.414 | |
Donor type Deceased Living |
20 (87) 3 (13) |
5 (83) 1 (17) |
>0.999 | |
Induction therapy Anti-thymocyte globulins Basiliximab No induction NA |
13 (57) 8 (35) 1 (4) 1 (4) |
4 (67) 1 (17) 1 (17) 0 (0) |
0.453 | |
Maintenance immunosuppression CNI (yes) MMF/MPA (mg/day) Steroids (mg/day) imTOR (yes) Belatacept (yes) |
22 (96) 1000 [500; 1000] 5.0 [0.0; 5.0] 1 (4) 1 (4) |
6 (100) 250 [0; 625] 2.5 [0.0; 5.0] 2 (33) 0 (0) |
>0.999 0.014 0.358 0.100 >0.999 |
|
Biological data Lymphocytes (G/L) Monocytes (G/L) CRP (mg/L) Albumin (g/L) Creatinine (μmol/L) |
1.16 [0.99; 1.38] 0.55 [0.41; 0.79] 4.0 [4.0; 5.8] 43 [42; 46] 134 [97; 183] |
1.99 [1.45; 2.66] 0.51 [0.44; 0.70] 4.5 [4; 10.6] 44 [43; 45] 131 [97; 237] |
0.069 0.723 0.570 0.874 0.859 |
*qualitative variables were compared using a Fisher or Chi-square test, quantitative variables were compared using a Mann-Whitney test. IQR: interquartile range; y, years; BMI, body mass index; NA, not available; CNI: calcineurin inhibitor; MMF/MPA: mycophenolate mofetil/mycophenolic acid; imTOR, inhibitor of the mechanistic target of rapamycin; CRP, C-reactive protein.