Table 1. Top 10 hits from the PLANTS virtual structure-based screen of e-Drug3D library of FDA approved drugs against the GBS BspC V-domain.
Rank | Score (%) | Name | MW |
---|---|---|---|
1 | 94.87 | Glycerol Phenylbutyrate | 530.63 |
2 | 94.20 | Cobicistat | 776.03 |
3 | 93.87 | Carfilzomib | 719.91 |
4 | 92.91 | Latanoprostene Bunod | 507.61 |
5 | 92.34 | Tafluprost | 409.44 |
6 | 92.29 | Venetoclax | 868.44 |
7 | 92.11 | Paliperidone Palmitate | 664.89 |
8 | 91.94 | Deferoxamine | 560.69 |
9 | 91.71 | Lapatinib | 581.06 |
10 | 91.54 | Fluphenazine Decanoate | 591.77 |