TABLE 1.
Demographic, clinical, and amyloid PET SUVR characteristics of the currently enrolled LEADS participants
| CN (N = 114) | EOAD (N = 170) | EOnonAD (N = 65) | EOAD vs CN, P‐value | EOnonAD vs CN, P‐value | EOAD vs EOnonAD, P‐value | |
|---|---|---|---|---|---|---|
| Age, y, mean (SD) | 55.93 (5.88) | 59.54 (3.77) | 57.91 (6.55) | <.0001 | .08 | .03 |
| Sex, % F | 60.81% | 50.75% | 33.96% | .1630 | .003 | .04 |
| Education, y, mean (SD) | 16.91 (2.12) | 15.34 (2.45) | 15.62 (2.52) | <.0001 | .002 | .47 |
| MMSE, mean (SD) | 29.25 (0.84) | 21.70 (4.68) | 26.10 (3.39) | <.0001 | <.0001 | <.0001 |
| CDR = 0.5, % | N/A | 56 | 81 | N/A | N/A | <.0001 |
| FBB SUVR, mean (SD) | 1.01 (0.07) | 1.54 (0.17) | 0.99 (0.06) | <.0001 | .11 | <0.0001 |