Copeland 2001.
Methods | RCT. | |
Participants | 229 Australian cannabis users. | |
Interventions | 1. 6‐session CBT (including elements of MI) (n= 78) 2. 1‐session CBT (including elements of MI) (n= 82) 3. delayed treatment control group (n= 69). |
|
Outcomes |
Physiological primary: None. Non‐physiological primary: Daily amount of cannabis use in last month, cannabis dependence, proportion of cannabis related problems. Secondary: None. |
|
Notes | ||
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | "...randomised to one of three conditions". |
Allocation concealment (selection bias) | Unclear risk | Insufficient information to permit judgment. |
Blinding (performance bias and detection bias) Patients and providers | Unclear risk | No blinding but the outcome measurements are not likely to be influenced by lack of blinding due to validation with physiological measurement. |
Blinding (performance bias and detection bias) Assessors | Low risk | "...follow‐up was conducted by an independent researcher "blind" to the subject's treatment allocation." |
Incomplete outcome data (attrition bias) All outcomes | High risk | 26% attrition at a median of 237 days follow‐up (individual follow‐up durations, range: 102‐553 days). Drop out was balanced across groups. No reasons for drop‐out were stated. "Analyses were conducted on an intention‐to‐treat basis." A best‐case scenario was reported. |
Selective reporting (reporting bias) | Low risk | The published report included all expected outcomes based on the study purposes. |
Other bias | High risk | 17% had sought assistance to moderate their use in the time between their participation in this study and follow‐up. They used urinalysis of cannabinoid levels as a validation of self‐reported cannabis use. Differences between groups at baseline were not reported. |