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. 2011 May 11;2011(5):CD008063. doi: 10.1002/14651858.CD008063.pub2

MarijuanaTP 2004.

Methods Multisite RCT (3 sites).
Participants 450 US cannabis dependent adults.
Interventions 1. 2 session MET (n= 146)
2. 9 session MET (n= 156)
3 4 month delayed treatment (n= 148).
Outcomes Physiological primary: None.
Non‐physiological primary: Percent of days smoking, periods smoked per day, joints per day, dependence symptoms, abuse symptoms, marijuana problems.
Secondary: None.
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Urn randomisation.
Allocation concealment (selection bias) Unclear risk Insufficient information to permit judgment.
Blinding (performance bias and detection bias) 
 Patients and providers Unclear risk No blinding but the outcome measurements are not likely to be influenced by lack of blinding due to validation with physiological measurement.
Blinding (performance bias and detection bias) 
 Assessors Unclear risk "Research assistants were not blinded to the participants' experimental conditions." But the outcome measurements are not likely to be influenced by lack of blinding due to validation with physiological measurement.
Incomplete outcome data (attrition bias) 
 All outcomes Low risk Loss to follow‐up at 4 months, 9 months and 15 months were 11%, 13% and 17%, respectively. Balanced. No reasons for loss reported. ITT performed (analysis of missing cases using baseline values.)
Selective reporting (reporting bias) Low risk The published report included all expected outcomes based on the study hypotheses.
Other bias Unclear risk Collateral interviews and urine specimens to check on self‐report. Numbers of sessions were confounded with differential content and process. Different expectancies of success were created by the differences in treatment length. There were no differences between groups at baseline.