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. 2011 May 11;2011(5):CD008063. doi: 10.1002/14651858.CD008063.pub2

Marsden 2006.

Methods Multisite RCT (5 sites).
Participants 342 UK adolescent and young adult stimulant users.
Interventions BMI (n= 166) vs written health risk information (n= 176).
Outcomes Physiological primary: None.
Non‐physiological primary: Ecstasy number of days, ecstasy tablets, cocaine powder number of days, cocaine g/day, crack number of days, crack g/day, cannabis number of days, cannabis g/day, alcohol number of days, alcohol g/weekday, alcohol g/weekend.
Secondary: None.
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk "two‐group randomised controlled trial".
Allocation concealment (selection bias) Unclear risk Insufficient information to permit judgment.
Blinding (performance bias and detection bias) 
 Patients and providers Unclear risk No blinding but the outcome measurements are not likely to be influenced by lack of blinding due to validation with physiological measurement.
Blinding (performance bias and detection bias) 
 Assessors Low risk "To guard against bias, all follow‐up interviews were conducted by a different worker from the one who administered the participant's recruitment protocol."
Incomplete outcome data (attrition bias) 
 All outcomes Low risk 13% attrition at 6 months follow‐up, balanced across conditions. Reasons not provided. "The analysis of outcome was conducted on an intention‐to‐treat (ITT) basis (involving all participants who were randomly assigned) and baseline scores were substituted for cases lost to follow‐up."
Selective reporting (reporting bias) Low risk The published report included all expected outcomes based on the study hypotheses.
Other bias Low risk Stimulant toxicology testing on a random 30%. There were no differences between groups at baseline. No additional sources of bias appear to be present.