Marsden 2006.
Methods | Multisite RCT (5 sites). | |
Participants | 342 UK adolescent and young adult stimulant users. | |
Interventions | BMI (n= 166) vs written health risk information (n= 176). | |
Outcomes |
Physiological primary: None. Non‐physiological primary: Ecstasy number of days, ecstasy tablets, cocaine powder number of days, cocaine g/day, crack number of days, crack g/day, cannabis number of days, cannabis g/day, alcohol number of days, alcohol g/weekday, alcohol g/weekend. Secondary: None. |
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Notes | ||
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | "two‐group randomised controlled trial". |
Allocation concealment (selection bias) | Unclear risk | Insufficient information to permit judgment. |
Blinding (performance bias and detection bias) Patients and providers | Unclear risk | No blinding but the outcome measurements are not likely to be influenced by lack of blinding due to validation with physiological measurement. |
Blinding (performance bias and detection bias) Assessors | Low risk | "To guard against bias, all follow‐up interviews were conducted by a different worker from the one who administered the participant's recruitment protocol." |
Incomplete outcome data (attrition bias) All outcomes | Low risk | 13% attrition at 6 months follow‐up, balanced across conditions. Reasons not provided. "The analysis of outcome was conducted on an intention‐to‐treat (ITT) basis (involving all participants who were randomly assigned) and baseline scores were substituted for cases lost to follow‐up." |
Selective reporting (reporting bias) | Low risk | The published report included all expected outcomes based on the study hypotheses. |
Other bias | Low risk | Stimulant toxicology testing on a random 30%. There were no differences between groups at baseline. No additional sources of bias appear to be present. |