Rohsenow 2004.
Methods | RCT. | |
Participants | 165 US cocaine dependent patients. | |
Interventions | 1. MET followed by group coping skills (n= 44) 2. MET followed by drug education (n= 39) 3. meditation relaxation followed by group coping skills (n= 44) 4. mediation relaxation followed by drug education (n= 38). |
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Outcomes |
Physiological primary: None. Non‐physiological primary: Number of cocaine use days, percentage of days alcohol used. Secondary: Readiness to change (Cocaine Change Assessment Questionnaire). Data not reported. Retention in treatment (days treated in partial hospital [data not reported]). |
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Notes | Results data are not available. Mail from Dr. Rohsenow May 19th 2010. | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | "Stratified randomisation balanced gender and cocaine use frequency." |
Allocation concealment (selection bias) | Unclear risk | Insufficient information to permit judgment. |
Blinding (performance bias and detection bias) Patients and providers | Unclear risk | No blinding but the outcome measurements are not likely to be influenced by lack of blinding due to validation with physiological measurement. |
Blinding (performance bias and detection bias) Assessors | Low risk | "Research assistants blind to treatment condition conducted assessments." |
Incomplete outcome data (attrition bias) All outcomes | Unclear risk | 10% attrition at 12 months follow‐up. We do not know the attrition at 3 and 6 months. Reasons for attrition unclear. Unclear if attrition was balanced across groups. Use of ITT was reported, but analyses were not reported with the full sample. |
Selective reporting (reporting bias) | Low risk | The published report included all expected outcomes based on the study hypotheses. |
Other bias | Unclear risk | Urine drug screens and collateral reports to check on self‐report. The MET group reported drinking on more days at baseline. |