Table 1.

The Demographics and Clinical Characteristics by Age Groups

Parameters	All Patients (n = 504)	≥60 Years (n = 392)	<60 Years (n = 112)	p
Age (years)	70.00 (62.00–76.00)	73.00 (67.00–78.00)	53.00 (49.00 −56.00)	< 0.001
Male, n (%)	286 (56.7)	207 (52.8)	79 (70.5)	0.001
Medical history, n (%)
Hypertension	336 (66.7)	276 (70.4)	60 (53.6)	0.001
Diabetes mellitus	71 (14.1)	59 (15.1)	12 (10.7)	0.245
Atrial fibrillation	269 (53.4)	242 (61.7)	27 (24.1)	< 0.001
TOAST classification, n (%)				< 0.001
Large-artery atherosclerosis	144 (28.6)	90 (23.0)	54 (48.2)
Cardioembolic	301 (59.7)	272 (69.4)	29 (25.9)
Undetermined or others	59 (11.7)	30 (7.7)	29 (25.9)
Occlusion site, n (%)				0.771
ICA	204 (40.5)	160 (40.8)	44 (39.3)
MCA	300 (59.5)	232 (59.2)	68 (60.7)
Baseline NIHSS score	14.00 (12.00–18.00)	15.00 (12.00–18.00)	14.00 (11.00–17.00)	0.022
Baseline ASPECT score	8.00 (8.00–10.00)	8.00 (8.00–9.00)	9.00 (8.00–10.00)	0.003
OTP (minutes)	280.00 (223.00–339.75)	280 (223.00–330.00)	276.50 (222.75–388.00)	0.294
Collateral circulation, n (%)				0.009
Grade 0	92 (18.3)	80 (20.4)	12 (10.7)
Grade 1	153 (30.4)	124 (31.6)	29 (25.9)
Grade 2	259 (51.4)	188 (48.0)	71 (63.4)
mTICI, 2b/3, n (%)	407 (80.8)	313 (79.8)	94 (83.9)	0.334
Unfavorable outcome	253 (50.2)	222 (56.6)	31 (27.7)	< 0.001
FBG (mmol/L)	6.08 (5.10–7.92)	6.31 (5.24–8.01)	5.52 (4.88–6.89)	0.002

Note: The values are presented as n (%), and median (interquartile range).

Abbreviations: ASPECT, Alberta Stroke Program Early CT; FBG, fasting blood-glucose; ICA, internal carotid artery; MCA, middle carotid artery; mTICI, modified thrombolysis in cerebral infarction; NIHSS, National Institutes of Health Stroke Scale; OTP, symptoms onset to groin puncture time; TOAST, the Trial of ORG 10172 in Acute Stroke Treatment.