Table 2.
Comparison of Clinical Characteristics in Those with Favorable versus Unfavorable Outcome of the Different Age Groups
| Parameters | Aged ≥60 Years | p | Aged <60 Years | p | ||
|---|---|---|---|---|---|---|
| Favorable Outcome (n = 170) | Unfavorable Outcome (n = 222) | Favorable Outcome (n = 81) | Unfavorable Outcome (n = 31) | |||
| Age (years) | 72.00 (66.00–76.00) | 74.50 (69.00–79.00) | < 0.001 | 53.00 (49.00–56.50) | 53.00 (48.00–56.00) | 0.527 |
| Male, n (%) | 99 (58.2) | 108 (48.6) | 0.060 | 61 (75.3) | 18 (58.1) | 0.073 |
| Medical history, n (%) | ||||||
| Hypertension | 110 (64.7) | 166 (74.8) | 0.030 | 42 (51.9) | 18 (58.1) | 0.555 |
| Diabetes mellitus | 17 (10.0) | 42 (18.9) | 0.014 | 9 (11.1) | 3 (9.7) | 0.826 |
| Atrial fibrillation | 88 (51.8) | 154 (69.4) | < 0.001 | 16 (19.8) | 11 (35.5) | 0.082 |
| TOAST classification, n (%) | 0.003 | 0.038 | ||||
| Large-artery atherosclerosis | 52 (30.6) | 38 (17.1) | 44 (54.3) | 10 (32.3) | ||
| Cardioembolic | 103 (60.6) | 169 (76.1) | 16 (19.8) | 13 (41.9) | ||
| Undetermined or others | 15 (8.8) | 15 (6.8) | 21 (25.9) | 8 (25.8) | ||
| Occlusion site, n (%) | 0.003 | 0.003 | ||||
| ICA | 55 (32.4) | 105 (47.3) | 25 (30.9) | 19 (61.3) | ||
| MCA | 115 (67.6) | 117 (52.7) | 56 (69.1) | 12 (38.7) | ||
| Baseline NIHSS score | 13.00 (11.00–16.00) | 16.00 (13.00–19.00) | < 0.001 | 13.00 (10.00–16.00) | 16.00 (12.00–20.00) | 0.006 |
| Baseline ASPECT score | 9.00 (8.00–10.00) | 8.00 (7.00–9.00) | < 0.001 | 9.00 (8.00–10.00) | 8.00 (7.00–9.00) | 0.001 |
| OTP (minutes) | 300.00 (230.00–330.00) | 270.00 (210.00–330.00) | 0.458 | 275.00 (222.50–420.00) | 280.00 (222.00–360.00) | 0.982 |
| Collateral circulation, n (%) | < 0.001 | < 0.001 | ||||
| Grade 0 | 6 (3.5) | 74 (33.3) | 5 (6.2) | 7 (22.6) | ||
| Grade 1 | 49 (28.8) | 75 (33.8) | 14 (17.3) | 15 (48.4) | ||
| Grade 2 | 115 (67.6) | 73 (32.9) | 62 (76.5) | 9 (29.0) | ||
| mTICI, 2b/3, n (%) | 152 (89.4) | 161 (72.5) | < 0.001 | 73 (90.1) | 21 (67.7) | 0.004 |
| FBG (mmol/L) | 5.54 (4.82–6.95) | 7.11 (5.81–9.14) | < 0.001 | 5.39 (4.83–6.58) | 6.06 (5.13–9.02) | 0.016 |
Note: The values are presented as n (%), and median (interquartile range).
Abbreviations: ASPECT, Alberta Stroke Program Early CT; FBG, fasting blood-glucose; ICA, internal carotid artery; MCA, middle carotid artery; mTICI, modified thrombolysis in cerebral infarction; NIHSS, National Institutes of Health Stroke Scale; OTP, symptoms onset to groin puncture time; TOAST, the Trial of ORG 10172 in Acute Stroke Treatment.