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. 2022 Mar 16;11:e71562. doi: 10.7554/eLife.71562

Appendix 2—table 2. Cumulative incidence estimates of heart diseases in breast cancer patients and age matched controls.

Cumulative incidence, % (95% CI)
6 months 1 year 2 years 5 years 10 years 15 years
Arrhythmia
Breast cancer 0.49 (0.35–0.66) 0.81 (0.63–1.02) 1.25 (1.02–1.52) 2.77 (2.41–3.16) 6.04 (5.49–6.63) 11.03 (10.04–12.08)
Matched control 0.20 (0.17–0.23) 0.38 (0.34–0.42) 0.79 (0.73–0.85) 2.18 (2.08–2.29) 4.98 (4.83–5.13) 8.21 (7.99–8.45)
Heart failure
Breast cancer 0.09 (0.04–0.18) 0.28 (0.18–0.42) 0.53 (0.38–0.71) 1.06 (0.85–1.32) 2.32 (1.98–2.70) 4.80 (4.13–5.54)
Matched control 0.05 (0.03–0.06) 0.10 (0.08–0.13) 0.22 (0.19–0.26) 0.68 (0.63–0.74) 1.87 (1.77–1.96) 3.78 (3.62–3.95)
Ischemic heart disease
Breast cancer 0.26 (0.17–0.40) 0.48 (0.35–0.65) 0.92 (0.73–1.16) 1.93 (1.64–2.27) 3.59 (3.17–4.05) 5.68 (4.98–6.44)
Matched control 0.13 (0.11–0.16) 0.33 (0.29–0.37) 0.72 (0.67–0.78) 1.91 (1.81–2.00) 3.85 (3.72–3.99) 5.90 (5.71–6.09)

Abbreviations: CI = confidence interval. Cumulative incidence estimates of heart diseases in all breast cancer patients (N = 8015) at different time-points following the index date ( = date of diagnosis in breast cancer patients). Cumulative incidence estimates are obtained from Aalen-Johansen estimation.