Figure 8. SNPs within the DNTT region that are associated with fewer N-insertions have a higher mean allele frequency within the ‘Asian’-associated PCA-cluster when compared to the population mean allele frequency computed across the 398 discovery cohort subjects (dashed, red horizontal line).

The p-values from a one-sample t-test (without Bonferroni multiple testing correction) for each PCA cluster compared to the population mean are reported at the top of the plot. The population mean is dominated by subjects in the ‘Caucasian’-associated PCA cluster (Figure 7—figure supplement 1).