TABLE 6.
Cost-effectiveness analysis in phase Ⅲ
| No | Medication combination | Hospitalization records (N) | Effective records (N) | Costs (CNY) | Total effective rate (effectiveness, E%) | Cost-effectiveness ratio (C/E) | Incremental cost-effectiveness ratio (△C/△E) |
|---|---|---|---|---|---|---|---|
| The whole group | |||||||
| 1 | PPC | 1,591 | 471 | 35,848.4 | 29.60 | 121,092.9 | 35,818.6 |
| Glutathione | 2,823 | 778 | 35,117.7 | 27.56 | 127,425.9 | ||
| 2 | PPC + magnesium isoglycyrrhizinate | 1,296 | 510 | 30,912.8 | 39.35 | 78,555.0 | −9,713.9 |
| Magnesium isoglycyrrhizinate | 1,828 | 651 | 31,276.1 | 35.61 | 87,823.0 | ||
| 3 | PPC + glutathione | 1,503 | 586 | 39,260.8 | 38.99 | 100,698.0 | −153,102.6 |
| Magnesium isoglycyrrhizinate + glutathione | 2,473 | 945 | 40,455.0 | 38.21 | 105,867.9 | ||
| Postoperation of nontumor/liver transplantation group | |||||||
| 1 | PPC | 813 | 393 | 37,966.7 | 48.34 | 78,541.7 | −24,507.2 |
| Glutathione | 1,260 | 504 | 40,010.6 | 40.00 | 100,026.5 | ||
| 2 | PPC + magnesium isoglycyrrhizinate | 720 | 389 | 33,103.7 | 54.03 | 61,271.6 | −49,406.1 |
| Magnesium isoglycyrrhizinate | 1,000 | 511 | 34,551.3 | 51.10 | 67,615.0 | ||
| 3 | PPC + glutathione | 613 | 273 | 43,619.9 | 44.54 | 97,945.1 | 66,834.5 |
| Glutathione | 1,291 | 504 | 39,944.0 | 39.04 | 102,316.8 | ||
| 4 | PPC + magnesium isoglycyrrhizinate | 517 | 276 | 38,730.8 | 53.38 | 72,550.1 | −210,830.3 |
| Magnesium isoglycyrrhizinate + glutathione | 969 | 491 | 44,444.3 | 50.67 | 87,711.8 | ||
| 5 | PPC + magnesium isoglycyrrhizinate + glutathione | 538 | 287 | 53,162.5 | 53.35 | 99,656.6 | 101,440.0 |
| Magnesium isoglycyrrhizinate + glutathione | 1,284 | 669 | 51,894.5 | 52.10 | 99,600.1 | ||
| Abnormal liver function group | |||||||
| 1 | PPC + magnesium isoglycyrrhizinate | 470 | 283 | 31,842.6 | 60.21 | 52,883.4 | 188,085.5 |
| Magnesium isoglycyrrhizinate | 470 | 294 | 36,243.8 | 62.55 | 57,940.8 | ||
| 2 | PPC + glutathione | 360 | 200 | 48,161.3 | 55.56 | 86,690.3 | 186,462.4 |
| Magnesium isoglycyrrhizinate + glutathione | 730 | 425 | 53,121.2 | 58.22 | 91,243.6 | ||
| 3 | PPC + magnesium isoglycyrrhizinate | 348 | 208 | 37,816.5 | 59.77 | 63,269.9 | −435,110.3 |
| Magnesium isoglycyrrhizinate + glutathione | 511 | 292 | 49,259.9 | 57.14 | 86,204.9 | ||
| 4 | PPC + magnesium isoglycyrrhizinate + glutathione | 361 | 188 | 48,996.1 | 52.08 | 94,082.9 | 189,558.8 |
| Magnesium isoglycyrrhizinate + glutathione | 800 | 433 | 52,863.1 | 54.12 | 97,668.6 | ||
Abbreviations: PPC, polyene phosphatidyl choline; CNY, China yuan; C, cost; E, effectiveness.