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Mutant genes of H. pylori isolated from 36 patients with unsuccessful prior eradication treatments.
| Antibiotic | Mutant genes | Genotypic resistance testing | |
|
| |||
| PCR, n (%) | WGS, n (%) | ||
| Clarithromycin | 23S rRNA | 32 (88.9) | 33 (91.7) |
| Amoxicillin | PBP-1A | 8 (22.2) | 8 (22.2) |
| Levofloxacin | gyrA | 17 (47.2) | 18 (50.0) |
| Metronidazole | rdxA | 16 (44.4) | 18 (50.0) |
| Tetracycline | 16S rRNA | 0 (NA) | 0 (NA) |
| Furazolidone | oorD/porD | 0 (NA) | 0 (NA) |
PCR, polymerase chain reaction; WGS, whole genome sequencing.
