TABLE 2.
Bayesian estimates of evolutionary and demographic parameters of major HIV-1 subtype B clades originated in the Amazonas state.
Clade | N | TMRCAa (95% HPD) | Reb (95% HPD) | |
BCAR–BR–I | 267 | 1978 (1970–1987) | 1978–1985 | 2.6 (0.2–4.6) |
1986–1993 | 2.5 (1.5–4.2) | |||
1994–2001 | 1.9 (1.2–3.0) | |||
2002–2009 | 1.9 (1.2–3.0) | |||
2010–2018 | 2.3 (1.5–3.5) | |||
BPAN–AM–I | 86 | 1988 (1981–1994) | 1988–1997 | 2.0 (0.5–4.1) |
1998–2007 | 2.9 (1.6–4.8) | |||
2008–2018 | 1.6 (1.1–2.6) | |||
BPAN–AM–II | 60 | 1995 (1990–2000) | 1995–2006 | 2.9 (1.6–5.4) |
2007–2018 | 2.2 (1.4–3.6) | |||
BPAN–BR–I–AM–I | 39 | 1998 (1992–2002) | 1998–2007 | 3.1 (1.6–5.6) |
2008–2018 | 2.1 (1.1–3.7) | |||
BPAN–BR–I–AM–II | 35 | 1998 (1992–2003) | 1998–2007 | 3.4 (1.7–5.9) |
2008–2018 | 1.9 (1.1–3.3) |
The table details the evolutionary and epidemiological parameters of the major HIV-1 subtype B clusters of pandemic (BPAN) and non-pandemic (BCAR) forms circulating in Brazil’s Amazonas state.
aMedian value and 95% HPD interval of the time to the most recent common ancestor (TMRCA).
bMedian value and 95% HPD interval of the effective reproductive number (Re) inferred in a bird-death statistical model.