Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Mar 7;13:773982. doi: 10.3389/fimmu.2022.773982

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 Cantoni, Mayora-Neto, Nadesalingam, Wells, Carnell, Ohlendorf, Ferrari, Palmer, Chan, Smith, Bentley, Einhauser, Wagner, Page, Raddi, Baxendale, Castillo-Olivares, Heeney and Temperton

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Neutralisation of SARS-CoV-2 pseudotypes by convalescent Serum from seropositive hospital patients and health care workers. Neutralisation assays were carried out using pseudotypes expressing either ancestral spike or B.1.1.298, B.1.1.7, B.1.617.2 K417N, B.1.617.2, B.1.617.1, P.1 and B.1.351. Data is presented in order of increasing fold changes (values in brackets) against the ancestral strain, revealing that VOCs B.1.351 and P.1 have the largest fold decreases (8.2 and 8.3 fold decrease respectively. Wilcoxon signed rank tests were used for statistical analysis between ancestral strain and each VOC (p = <0.001). Black lines denote geometric means. Blue circles represent samples derived from patients, red circles represent samples derived from previously infected healthcare workers. ***p=<0.001).