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. 2022 Mar 7;13:835677. doi: 10.3389/fmicb.2022.835677

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Copyright © 2022 Cavaco, Castanho and Neves.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Structure of an antibody-antibiotic conjugate and general characteristics of (i) the target antigen, (ii) the antibody, (iii) the linker, and (iv) the antibiotic. DAR, drug-antibody ratios; PK, pharmacokinetic; PD, pharmacodynamic.