Table II.
Unadjusted Analysis: Clinical Characteristics and Growth Rate
| Clinical Characteristic | AAA Growth Rate without Clinical Characteristic (cm/yr) | Change in Growth Rate with Clinical Characteristic (cm/yr) | Clinical Characteristic*time p-value |
|---|---|---|---|
| Randomized Doxycycline Rx | 0.19 | 0.01 | 0.43 |
| Diabetes | 0.21 | −0.06 | <0.0001 |
| Female sex | 0.21 | −0.02 | 0.01 |
| Smoking current | 0.19 | 0.05 | 0.0001 |
| Smoking former | 0.19 | −0.02 | 0.66 |
| COPD | 0.19 | 0.00 | 0.24 |
| ARB therapy | 0.20 | −0.06 | <0.0001 |
| Statin therapy | 0.22 | −0.03 | <0.0001 |
| Beta blocker therapy | 0.20 | −0.01 | 0.22 |
| BMI (per kg/m2) | −0.0019 | <0.01 | |
Unadjusted associations of clinical characteristics and the AAA growth rate in the N-TA3CT. Mean growth rates as calculated by linear regression. P-values presented for each clinical characteristic are derived from a linear mixed effects model on AAA growth. BMI is treated as a continuous variable – the effect on the AAA growth is presented as a linear coefficient.