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. Author manuscript; available in PMC: 2023 Apr 1.
Published in final edited form as: Expert Opin Drug Saf. 2021 Oct 20;21(4):477–486. doi: 10.1080/14740338.2022.1989409

Table 2:

Summarized table of Elagolix/ABT prescribed to women with uterine fibroids

Product Elagolix/E2/NETA (300 mg/1 mg/0.5 mg) in the morning and Elagolix 300 mg in the evening
Common adverse events Hot flushes
Headache
Metrorrhagia
Precaution Liver diseases- Deep venous thrombosis- Hormonal dependent malignancies- Cardiac disorder- irregular bleeding- gall bladder disorders
Contraindications Osteoporosis- uncontrolled hypertension- pregnancy- current liver or heart disease- current hormonal dependent malignancy.
Drug interactions Strong CYP3A4 inducers and inhibitors
OATP1B1 inhibitors
CYP2C19 substrates
P-glycoprotein substrates