. Author manuscript; available in PMC: 2022 Apr 1.

Published in final edited form as: J Neurosci Res. 2022 Feb 20;100(4):1047–1062. doi: 10.1002/jnr.25018

TABLE 2.

Moderated mediation model shows how clinical pain influences different functional connectivity, mediated through pain catastrophizing and moderated by ethnicity/race

Outcome functional connectivity	WOMAC → Catas (path a)	Catas → Functional connectivity (path b₁)	WOMAC → Functional connectivity (path c₁′)	WOMAC → Ethnicity/Race → Functional connectivity (path c₂′)	Catas → Ethnicity/Race → Functional connectivity (path b₂)
Outcome functional connectivity	B(SE)	B(SE)	B(SE)	B(SE)	B(SE)
ACC	0.139^* (0.022)	0.003 (0.009)	0.002 (0.003)	−0.004 (0.005)	0.034 (0.018)
dIPFC	0.139^* (0.022)	−0.007 (0.007)	0.000 (0.002)	−0.010^* (0.004)	0.049^* (0.014)
Insula	0.139^* (0.022)	−0.012 (0.008)	0.002 (0.002)	−0.004 (0.005)	0.037^* (0.016)
SI	0.139^* (0.022)	−0.006 (0.010)	−0.001 (0.003)	−0.006 (0.005)	0.049^* (0.018)

Note: S1 = Primary Somatosensory Cortex. Covariates include study site, age, sex, and education.

Abbreviations: ACC, anterior cingulate cortex; Catas, pain catastrophizing; dlPFC, dorsolateral prefrontal cortex; WOMAC, Western Ontario and McMaster Universities Osteoarthritis Index.

Present if bootstrap confidence interval does not include zero and is considered statistically significant.