Skip to main content
. Author manuscript; available in PMC: 2022 Sep 1.
Published in final edited form as: Nat Med. 2022 Mar;28(3):427–428. doi: 10.1038/s41591-022-01684-8

Figure 1. Time course of SARS-CoV-2 infection.

Figure 1.

Typical time course from initial SARS-COV-2 infection to severe COVID-19 (A) and schematic (B) depicting the time course of SARS-CoV-2 infection within lung acinar units. End-stage pulmonary disease is associated with dead alveolar cells, dead epithelial stem cells, demarginated endothelial cells and neutrophils expressing increased PAI-1, widespread clotting, and severe pulmonary fibrosis.