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. Author manuscript; available in PMC: 2023 Mar 1.
Published in final edited form as: Genesis. 2022 Feb 18;60(3):e23468. doi: 10.1002/dvg.23468

Figure 2.

Figure 2

Wnt1-Cre2 activity is detectable in adult male germ cells

Testes from adult male ROSA26mTmG/+; Wnt1-Cre2Tg/+ and ROSA26mTmG/+; Wnt1-CreTg/+ mice were sectioned and stained with DAPI and phalloidin. EGFP signal indicating CRE activity was found extensively within the seminiferous tubules of Wnt1-Cre2 but not Wnt1-Cre mice. Somatic tissue outside the tubules remained negative for EGFP and positive for tdTomato, indicating that Wnt1-Cre2 is active in the adult male germline but not somatic tissue within the testis. At 2.5x scale bars represent 500 μm. At 20x scale bars represent 50 μm.