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. Author manuscript; available in PMC: 2023 Mar 1.
Published in final edited form as: Genesis. 2022 Feb 18;60(3):e23468. doi: 10.1002/dvg.23468

Figure 3.

Figure 3

The Wnt1-Cre2 transgene inserted among genes expressed in the male germline

(A) Wnt1-Cre2 inserted at the E2f1 locus in a complicated rearrangement involving a large duplication and inversion (green stars) enclosing a smaller deletion (magenta stars) where 1–3 copies of the transgene itself inserted. The Wnt1-Cre2 transgenic locus is depicted at bottom. This panel is based on Figure 3 from Goodwin et al. (B) Several genes near the insertion site are expressed or enriched in the testis relative to other organs. (C) E2f1 expression is enriched in spermatogonia and nearby Actl10 and 170000F12Rik are enriched in spermatids.