Table 3.

Sensitivity analyses evaluating body mass index and sex in relation to fatty infiltration in the ROW cohort.

Unadjusted
	N-cases/N-controls	FI (Grade 1 or higher)		N-cases/N-controls	FI (Grade 2 or higher)
Variable		OR	95% CI		OR	95% CI
Body mass index (BMI)
BMI (continuous)	58/96	1.02	(0.97, 1.08)	42/96	1.03	(0.97, 1.10)
BMI <25	9/24	1.00	(Ref)	4/24	1.000	(Ref)
BMI 25–30	23/31	1.98	(0.78, 5.05)	20/31	3.87	(1.17, 12.83)
BMI > 30	26/41	1.69	(0.68, 4.20)	18/41	2.63	(0.80, 8.70)
Sex (Female vs. Male [ref])	58/96	0.95	(0.51, 1.82)	42/96	0.70	(0.33, 1.46)
Multivariable Adjusted
	N-cases/N-controls	FI (Grade 1 or higher)		N-cases/N-controls	FI (Grade 2 or higher)
Variable		OR	95% CI		OR	95% CI
Body mass index (BMI)
BMI (continuous)	44/82	1.051	(0.963, 1.148)	31/82	1.08	(0.98, 1.21)
BMI <25	7/22	1.000	(Ref)	2/22	1.00	(Ref)
BMI 25–30	19/27	1.097	(0.254, 4.748)	16/27	2.52	(0.25, 25.76)
BMI > 30	18/33	3.116	(0.773, 12.558)	13/33	7.81	(0.84, 72.28)
Sex (Female vs. Male [ref])	44/82	3.592	(1.148, 11.245)	31/82	2.38	(0.59, 9.58)

FI = fatty infiltration defined either as grade 1 or higher level of fatty infiltration in the Goutallier scale; or as grade 2 or higher level of fatty infiltration in the Goutallier scale; Odds ratios (OR) and 95% Confidence interval (95% CI) were estimated using logistic regression using BMI (continuous) or BMI (categorical) and sex, while adjusting for age at MRI, cross sectional area of tear, and duration of tear for multivariable model. Unadjusted model only included BMI (continuous or categorical) or sex with FI.