Fig. 1.

Schematic representation of the excellent performance of the NNH patches and their application to diabetic wound. a) The self-healing and temperature-responsive performances of NNH patches, b) The patches for treatment of diabetic wound. c) Schematic illustration of the mechanism of NNH patch in promoting diabetic wound healing: 1) NNH facilitated the migration of epithelial cells by created moist environment. 2) The patch improved the undesirable collagen deposition. 3) The patch controlled wound infection by down-regulating inflammatory factors and 4) promoted the reconstruction of the blood vessels and microcirculation by delivering VEGF to wounds.