Table 1.
Patient characteristics | Value |
---|---|
Age | |
Median (range) Age ≥ 65 years, n (%) |
71 (48–88) 49 (74.2) |
PSA (ng/mL) | |
Median (range) | 145 (7–9579) |
ALP (U/L) | |
Median (range) | 112 (35–1753) |
Hemoglobin (g/dL) | |
Median (range) < 13 g/dL, n (%) |
12 (6–16) 44 (66.7) |
ECOG performance status, n (%) | |
0 1 ≥ 2 |
17 (25.8) 31 (47.0) 18 (27.3) |
Sites of metastases, n (%) | |
Bone Lymph node Liver Other |
62 (93.9) 49 (74.2) 12 (18.2) 16 (24.2) |
Prior therapies, n (%) | |
Prostatectomy Radiation ADT NAAD Abiraterone Enzalutamide Abiraterone and enzalutamide Chemotherapy Docetaxel Cabazitaxel Docetaxel and cabazitaxel [223Ra]Ra-dichloride Other |
32 (48.5) 41 (62.1) 66 (100) 65 (98.5) 50 (75.8) 54 (81.8) 39 (59.1) 47 (71.2) 46 (69.7) 21 (31.8) 20 (30.3) 14 (21.2) 11 (16.7) |
PSA, prostate-specific antigen; ALP, alkaline phosphatase; ECOG, Eastern Cooperative Oncology Group; ADT, androgen deprivation therapy; NAAD, novel androgen axis drugs