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. 2022 Mar 22;12:4862. doi: 10.1038/s41598-022-08952-0

Table 1.

Baseline characteristics of individuals with chronic obstructive pulmonary disease consulting or hospitalized for influenza-like illness according to the result of the influenza test.

Laboratory-confirmed influenza cases
n (%)
Influenza-negative controls
n (%)
p value
Total 542 (100) 1219 (100)
Age groups (years) 0.047
25–64 143 (26) 261 (21)
65–84 313 (58) 729 (60)
≥ 85 86 (16) 229 (19)
Sex 0.029
Male 362 (67) 877 (72)
Female 180 (33) 342 (28)
Healthcare setting < 0.001
Primary healthcare 92 (17) 72 (6)
Hospital 450 (83) 1147 (94)
Other major chronic conditions
Diabetes 147 (27) 395 (32) 0.027
Cancer 148 (27) 367 (30) 0.233
Liver cirrhosis 34 (6) 94 (8) 0.283
Renal disease 91 (17) 228 (19) 0.336
Immunodeficiency 16 (3) 32 (3) 0.697
Asthma 50 (9) 90 (7) 0.187
Cardiovascular disease 180 (33) 483 (40) 0.010
Dementia 10 (2) 38 (3) 0.130
Stroke 38 (7) 95 (8) 0.566
Rheumatic disease 19 (4) 33 (3) 0.361
Severe obesity 25 (5) 50 (4) 0.624
Vaccination in the current season < 0.001
No 233 (43) 387 (32)
Yes 309 (57) 832 (68)
Influenza vaccines in the 5 prior seasons < 0.001
0 166 (31) 251 (21)
1–2 69 (13) 146 (12)
3–5 307 (56) 822 (67)
Influenza season < 0.001
2015–2016 80 (14) 150 (12)
2016–2017 102 (19) 181 (15)
2017–2018 161 (30) 242 (20)
2018–2019 123 (23) 288 (24)
2019–2020 76 (14) 358 (29)