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. 2022 Mar 22;12:4854. doi: 10.1038/s41598-022-08131-1

Table 2.

Association of recovery status (recovered or relapsed) with relative changes in feeding and activity behaviors of dairy calves (n = 19 matched pairsa) in the 10 days after initial Bovine Respiratory Disease diagnosis and antimicrobial therapy on d 0.

Variable Recovered Relapsed SEM F-valued P-value (recovery status)c P-value (recovery status * day)
Relative change milk intake % 96.66 101.13 3.01 1.001,17 0.33 0.91
Relative change drinking speed % 114.24 89.96 5.11 10.181,16 0.01 0.22
Relative change rewarded visits % 105.58 110.07 4.24 0.501,16 0.49 0.17
Relative change unrewarded visits % 105.31 103.27 1.95 0.541,18 0.47 0.62
Relative change starter intake % 125.81 104.70 4.34 10.441,17 0.01 0.32
Relative change lying time % 95.48 98.81 0.90 6.701,17 0.01 0.05
Relative change lying bouts % 112.28 107.04 3.18 1.321,17 0.27 0.20
Relative change step count % 229.81 185.96 27.61 1.241,18 0.28 0.01
Relative change acceleration activity indexd % 216.36 168.11 22.38 2.281,18 0.15 0.01

Relative changes referred to day 0 as a baseline. Feeding behaviors (average drinking speed, milk intake, and number of rewarded visits) were recorded by an automated milk feeder from calves offered 10 L of milk replacer/day, and activity measures (lying time, step count, acceleration activity indexb and lying bouts) were recorded by a pedometer. Results are reported as least squares meansc.

aAll calves were pair matched to healthy calves by age at diagnosis, birthdate, and gender. Bovine Respiratory Disease was defined as a clinical score of at least 526 and lobar lung consolidation27.

bThe acceleration activity index was generated by the commercial software algorithm (IceRobotics, Scotland) based on a calf’s daily average acceleration rate and step count.

cSignificance are in bold P < 0.05.

dSuperscripts refer to numerator and denominator degrees of freedom.